Cardiorenal medicine – new targets, treatments and technologies

17th Annual Scientific Meeting of the Cardiorenal Forum

'Cardiorenal medicine – new targets,
treatments and technologies'

took place on Friday 7th October 2022 in London


This independent meeting was supported and funded by the following pharmaceutical companies: A Menarini Farmaceutica UK Ltd, Astellas Pharma Ltd, AstraZeneca UK Ltd, Bayer plc, CSL Vifor, GSK, Novo Nordisk Ltd, and Sanofi.


Videos from our popular 17th Annual Scientific Meeting are available below.

The meeting promoted and shared academic interest across the cardiorenal spectrum of disease taking in new targets, treatments and technologies in diabetes, heart failure, kidney transplantation, and chronic kidney disease.

Watch our state-of-the-art presentations with interactive discussion and case-based learning given by our expert faculty. Please note: CPD credits are no longer available.




















Session 6 is unavailable.





Is it for me?

These videos are for healthcare professionals only and are aimed at anyone treating the cardiorenal patient particularly those working in heart failure, cardiology, nephrology, diabetes, lipids, endocrinology, care of the elderly, general medicine, general practice, clinical pharmacy and allied disciplines.
Feedback from past delegates has been very positive with 98% of delegates at our last meeting saying the meeting was clinically excellent or good.

Academic endorsement

This year’s meeting has been endorsed by The British Society for Heart Failure (BSH), the Irish Nephrology Society, Kidney Disease Improving Global Outcomes (KDIGO), and the UK Kidney Association (UKKA).




Programme

Session 1. What’s new in transplantation
  Chair: Professor Philip Kalra, Consultant Nephrologist, Salford Royal NHS Foundation Trust; Professor of Renal Medicine, University of Manchester
Effects of live-donor nephrectomy on cardiovascular function Dr Anna Price, Specialist Registrar in Renal Medicine, Queen Elizabeth University Hospital, Birmingham
What’s new in advanced heart failure care (mechanical circulatory support, and cardiac transplantation) and when to consider it Dr Jayan Parameshwar, Consultant Cardiologist, Royal Papworth Hospital NHS Foundation Trust, Cambridge
Discussion
Session 2. Diabetes, obesity and cardiorenal disease
  Chair: Dr Caroline Day, Visiting Fellow, School of Life and Health Sciences, Aston University, Birmingham
Diabetes guidelines: choosing the right drugs for the right patients Professor Cliff Bailey, Emeritus Professor, School of Life and Health Sciences, Aston University, Birmingham
Weight loss to improve microvascular function Dr Safwaan Adam, Consultant Endocrinologist, The Christie NHS Foundation Hospital, Manchester
Discussion
Session 3. Anaemia and iron deficiency in cardiorenal disease
  Chair: Professor Paul Kalra, Consultant Cardiologist, Portsmouth Hospitals University NHS Trust
Iron deficiency anaemia – rationale for studies in cardiorenal patients Dr Sharlene Greenwood, President, UK Kidney Association; NIHR Advanced Research Fellow, and Consultant Physiotherapist, King’s College Hospital, London
Hypoxia-inducible factor stabilisers (HIF) in renal anaemia Professor Jonathan Barratt, The Mayer Professor of Renal Medicine, University of Leicester
Discussion
SANOFI-SPONSORED SYMPOSIUM. Progress in Fabry disease
  Chair: Professor Smeeta Sinha, Consultant Nephrologist, Salford Royal NHS Foundation Trust
Speakers
Dr Luis Lopes, Consultant Cardiologist, Barts Health NHS Trust, London
Dr Shabbir Moochhala, Consultant Nephrologist, Royal Free Hospital, London
Session 4. British Society for Heart Failure lecture
  Chairs: Dr Lisa Anderson, Heart Failure Consultant, Cardiovascular Clinical Academic Group, St George's University Hospitals NHS Foundation Trust, London
Diabetic cardiomyopathy – advances in understanding Professor Gerry McCann, NIHR Research Professor (Experimental Medicine) and Professor of Cardiac Imaging, University of Leicester
Discussion
Session 5. Cardiorenal clinical trial update
  Chair: Professor Derek Yellon, Professor of Molecular and Cellular Cardiology, University College London; Director of the Hatter Cardiovascular Institute, London
Cardiology trials update Dr Geraint Morton, Consultant Cardiologist, Portsmouth Hospitals University NHS Trust
Renal trials update Dr David Lappin, Consultant Nephrologist and General Physician, Galway University Hospitals
Discussion
Session 6. The multimorbidity MDT
  Chair: TBC
The need for an MDT (and teasing out ‘unknown CKD’) Professor Smeeta Sinha, Consultant Nephrologist, Salford Royal NHS Foundation Trust; Honorary Lecturer, University of Manchester
Discussion
Session 7. Interactive clinical cases in cardiorenal disease
  Moderators: Dr Sarah Birkhoelzer, Cardiology Registrar, Radcliffe Department of Medicine, Oxford; Professor Paul Kalra, Consultant Cardiologist, Portsmouth Hospitals University NHS Trust; Professor Philip Kalra, Consultant Nephrologist, Salford Royal NHS Foundation Trust; Professor of Renal Medicine, University of Manchester
Case 1: Anticoagulation in CKD Miss Kathrine Parker, Specialist Renal Pharmacist and NIHR Clinical Doctoral Fellow, Manchester University NHS Foundation Trust
Case 2: Dyslipidaemia in high-risk patients – new treatment options Dr Wei Yang, Registrar in Metabolic Medicine, Imperial College London
Case 3: Finerenone in CKD Dr Kieran McCafferty, Consultant Nephrologist, Barts Health NHS Trust, London
Summing up

Dr Safwaan Adam Consultant Endocrinologist, The Christie NHS Foundation Hospital, Manchester

Safwaan Adam graduated from the University of Cape Town (South Africa) following which he had postgraduate training in South Africa, New Zealand and the United Kingdom. He completed his training in Diabetes and Endocrinology in the North West of England where he had also undertaken research in obesity at the University of Manchester. His research has been particularly focused on the role of bariatric surgery in managing the microvascular complications of diabesity. He has also studied the role of bariatric surgery in preventing cardiovascular disease and has won a number of awards for his work. He is actively involved in medical education and has been invited to speak at key national and international conferences.

Dr Lisa Anderson Heart Failure Consultant, Cardiovascular Clinical Academic Group, St George's University Hospitals NHS Foundation Trust, London

To come

Professor Cliff Bailey Emeritus Professor, School of Life and Health Sciences, Aston University, Birmingham

Cliff Bailey is Emeritus Professor of Clinical Science at Aston University in Birmingham, England. He has served on committees of Diabetes UK, Society for Endocrinology, and EASD, and has held various editorial positions - presently senior editor of DVDRes. He has been an expert witness for drug licensing authorities, regulatory agencies and other national and international review bodies. He received the 2013 Lunar Society medal and the 2015 Banting Lecture award. His research is mainly directed towards the pathogenesis and treatment of type 2 diabetes, on which he has published over 400 research papers and reviews.

Professor Jonathan Barratt The Mayer Professor of Renal Medicine, University of Leicester

Jonathan Barratt leads the Renal Research Group within the College of Life Sciences, University of Leicester. His research interests span a range of areas across renal medicine and include glomerular disease, multi-system renal disease and complications of chronic kidney disease, in particular renal associated anaemia.

Dr Sarah Birkhoelzer Cardiology Registrar, Radcliffe Department of Medicine, Oxford

Sarah Birkhoelzer is a Wessex Cardiology Registrar with a subspecialty interest in heart failure and cardiovascular imaging. She is currently out of programme as a Clinical Research Fellow at Oxford Centre for Clinical Magnetic Resonance Research, John Radcliffe Hospital, Oxford, where she does a PhD with a focus on cardiometabolic changes in heart disease. As the past British Junior Cardiologist’s Association Women in Cardiology representative she is now part of the BCS Women in Cardiology Committee promoting gender equality and equal opportunities in Cardiology.

Dr Caroline Day Visiting Fellow, School of Life and Health Sciences, Aston University, Birmingham

Caroline Day is director of Med Ed UK. She has worked in a range of educational and healthcare settings and was an inaugural editor (2001-2014) of the British Journal of Diabetes & Vascular Disease (now British Journal of Diabetes). Dr Day is a committee member (former Chair) and Fellow of the Royal Society of Biology and a Visiting Fellow with the Aston University Diabetes Group. Her specialist research interest is the evaluation of traditional medicines to treat diabetes, she has over 100 research papers, reviews, book chapters and on-line reference texts, mostly on treating type 2 diabetes and obesity.

Dr Sharlene Greenwood President, UK Kidey association, NIHR Advanced Research Fellow, and Consultant Physiotherapist, King’s College Hospital, London

Sharlene Greenwood is a Consultant Physiotherapist at King’s College Hospital, an Honorary Reader in Exercise and Lifestyle Medicine at King’s College London, and a NIHR post-doctoral research fellow. She co-chairs the UK Kidney Research Consortium and is the President of the UK Kidney Association. Sharlene has worked with people living with kidney disease for over 15 years, mostly designing and evaluating different ways to motivate people to be more active. Most recently, Sharlene led on the development of Kidney Beam www.beamfeelgood.com, a novel digital platform that was rapidly developed to help people living with kidney disease manage their physical and emotional wellbeing during the COVID pandemic and beyond. Sharlene leads one of the only commissioned renal exercise services in the UK, which includes renal rehabilitation, weight management, and specialist kidney transplant exercise clinics.

Professor Paul Kalra Consultant Cardiologist, Portsmouth Hospitals University NHS Trust

Paul Kalra is a Consultant Cardiologist at Portsmouth Hospitals University NHS Trust, and an Honorary Professor of Cardiology. His research interests include the role of iron deficiency and its correction in patients with heart failure, cardiorenal disease and the impact of hyperkalaemia on RAAS inhibition use. He is one of the founders of the Cardiorenal Forum and past Chair of the British Society for Heart Failure

Professor Philip Kalra Consultant Nephrologist, Salford Royal NHS Foundation Trust; Professor of Renal Medicine, University of Manchester

Philip Kalra graduated from Cambridge University and is Professor of Nephrology in Salford and the University of Manchester. He has been a Consultant Nephrologist since 1995, working at the Salford Royal NHS Foundation Trust. He has major research focus on renovascular disease, cardiovascular disease in chronic kidney disease (CKD), CKD progression and iron use in CKD, and he leads the research team in Salford. He was Academic Vice President of the UK Renal Association from 2016–19, Chair of the UK Kidney Research Consortium during this time and was Chair of the NIHR CRN Renal Disorders group from 2010–18. He has been involved in the development of several large UK clinical trials in nephrology and cardiology, including the ASTRAL, PIVOTAL and IRONMAN trials, and he has played a role in amalgamating Cardiorenal education and research within the UK

Dr David Lappin Consultant Nephrologist and General Physician, Galway University Hospitals

David Lappin graduated in Dublin in 1991. He trained in nephrology in Dublin and Manchester and obtained a PhD in Medicine in 2002. He is a Consultant Nephrologist/Honorary Personal Professor of Nephrology at Galway University Hospitals/National University of Ireland, Galway. His areas of interest are clinical nephrology, diabetic nephropathy and resistant hypertension. He is the Treasurer of the European Union of Medical Specialists Section of Nephrology, the current UEMS lead, exam board and standard setting group member of the European Specialty Examination in Nephrology, and former member of the European Renal Association CME sub-committee.

Dr Luis Lopes Clinical/Academic Consultant Cardiologist, Barts Heart Centre, London

As well as his role at the Barts Heart Centre, Luis Lopes is also Assistant Professor at the Centre for Heart Muscle Disease, Institute of Cardiovascular Science, UCL, and the cardiology lead for the North Thames Genomic Laboratory Hub (part of the NHS Genomic Medicine Service). His main clinical focus is genetic cardiomyopathies including hypertrophic, dilated, arrhythmogenic and metabolic cardiomyopathies including Fabry disease; cardiac involvement in neuromuscular conditions and mitochondrial cardiomyopathy. Major research interests include the discovery of new genetic causes of cardiomyopathy and the use of advanced imaging in the construction of genotype-phenotype models.

Dr Kieran McCafferty Consultant Nephrologist, Barts Health NHS Trust, London

Kieran McCafferty is a Consultant Nephrologist at Barts Health National Health Service Trust and Senior Lecturer at Queen Mary University London. He is an active clincal trialist in the field of CKD, CVD and Diabetes.

Professor Gerry McCann NIHR Research Professor (Experimental Medicine) and Professor of Cardiac Imaging, University of Leicester

Gerry McCann is a NIHR Research Professor/Professor of Cardiac Imaging and Honorary Consultant Cardiologist at the University of Leicester and is the Cardiovascular theme lead for the NIHR Leicester Biomedical Research Centre.

Gerry was a full-time NHS consultant cardiologist before undertaking successive NIHR research fellowships since 2011. Prof. McCann directs a very active clinical imaging research programme with funding from the British Heart Foundation, MRC and his NIHR Research Professorship is focused on the prevalence of heart failure in a multi-ethnic population withT2D and how best to diagnose and prevent symptom onset, working closely with researchers from the Leicester Diabetes Centre.

Dr Shabbir Moochhala Consultant Nephrologist, Royal Free Hospital, London

Shabbir Moochhala trained in Edinburgh and Newcastle upon Tyne. He has expertise in rare renal diseases and is a principal investigator for a number of international research trials. He is also a general physician. He has a specialist interest in Fabry nephropathy and renal tubular disease, and with colleagues runs a dedicated clinic for Fabry patients with renal disease at the Royal Free Hospital, as part of the Lysosomal Storage Disorders Unit.

Dr Geraint Morton Consultant Cardiologist, Portsmouth Hospitals University NHS Trust

Geraint Morton was appointed a Consultant Cardiologist at Portsmouth Hospitals University NHS Trust in 2014. He trained in cardiology in Wessex and also completed a clinical research PhD in cardiac MRI at King’s College London. His subspecialty interests are heart failure and complex devices. He is Clinical Lead for the Heart Failure and Implantable Devices Services at Portsmouth Hospitals University NHS Trust. He has published widely in his fields of interest, most recently focusing on multidisciplinary working and pathways of care in heart failure.

Dr Jayan Parameshwar Consultant Cardiologist, Royal Papworth Hospital NHS Foundation Trust, Cambridge

Jayan Parameshwar is a Consultant Cardiologist and has been associated with the Advanced Heart Failure and Heart Transplant programme at Papworth Hospital for over 30 years. He has been involved with all aspects of transplantation in the UK for many years and was a member of the Cardiothoracic Advisory Group at NHSBT for about 15 years. From May 2018 to May 2021 he was Chair of this group. He has served on the Board of Directors of the International Society for Heart and Lung Transplantation and as Associate Editor of the Journal of Heart and Lung Transplantation.

Miss Kathrine Parker Specialist Renal Pharmacist and NIHR Clinical Doctoral Fellow, Manchester University NHS Foundation Trust

Kathrine Parker has worked as a specialist renal pharmacist at Manchester University NHS Foundation trust since 2010. In 2016 she completed her Masters in clinical pharmacy. She has had a longstanding interest in anticoagulation in chronic kidney disease (CKD) with a number of publications and presentations in this field. In 2019 she received a personal funding award from the NIHR to investigate anticoagulant use in CKD as part of a clinical academic doctoral fellowship. Kathrine also currently sits on the UKKA clinical guideline committee and is co-chair of a workstream within the UKKA supportive care special interest group (SIG).

Dr Anna Price Specialist Registrar in Renal Medicine, Queen Elizabeth University Hospital, Birmingham

Anna Price is a Speciality Registrar in Renal Medicine training within the West Midlands. She was awarded a British Heart Clinical Training Fellowship and completed her PhD at the University of Birmingham in 2021. Her research interests are in the cardiovascular consequences of renal disease and cardiac magnetic resonance imaging.

Professor Smeeta Sinha Consultant Nephrologist, Salford Royal NHS Foundation Trust; Honorary Lecturer, University of Manchester

Smeeta Sinha is a Consultant Nephrologist at Salford Royal Hospital and an Honorary Senior Lecturer at the University of Manchester. She is also a Northern Care Alliance Research & Innovation Deputy Director and the Chronic Kidney Disease National Clinical Advisor to the NHS England national Renal Service Transformation Programme. Smeeta’s clinical interests are in CKD, and multi-morbidity including diabetic kidney disease. Smeeta’s research interests include vascular calcification, multi-morbidity, glomerulonephritis and rare renal diseases.

Dr Wei Yang Registrar in Metabolic Medicine, Imperial College London

To come

Professor Derek Yellon Professor of Molecular and Cellular Cardiology, University College London; Director of the Hatter Cardiovascular Institute, London

Derek Yellon is Professor of Molecular & Cellular Cardiology at University College London (UCL) & Director of the Hatter Cardiovascular Institute UCL & UCLH. He is also a Hon Professor of Medicine in the Department of Medicine at the University of Cape Town and holds Honorary Chairs at the University of South Alabama in the USA, and the North China Coal Medical University in China.

He has published in excess of 600 full papers and edited 23 books. He runs a translational research Institute whose interest relates to the pathophysiology of acute MI & cardioprotection in the setting of diabetes, ischaemia/reperfusion injury & molecular aspects of ischaemic injury in both the basic and clinical arena.